Medical Student: Mohammad Husein Group: M1436 To: Dr.Igor Cemortan Mitosis: -division of somatic (body) cells Meiosis -division of gametes (sex… [602005]

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Medical Student: [anonimizat]: M1436
To: Dr.Igor Cemortan

Mitosis:
-division of somatic (body) cells
Meiosis
-division of gametes (sex cells)

Interphase
Prophase
Metaphase
Anaphase
Telophase

Interesting things happen!
1.Cell preparing to divide
2.Genetic material doubles

Chromosome pair up !
1.Chromosomes thicken and shorten
-become visible
-2 chromatids joined by a centromere
2.Centrioles move to the opposite sides of the
nucleus
3.Nucleolus disappears
4.Nuclear membrane disintegrate

Chromosomes meet in the middle !
1.Chromosomes arrange at equator of cell
2.Become attached to spindle fibres by
centromeres
3.Homologous chromosomes do not associate

Chromosomes get pulled apart
1.Spindle fibres contract pulling chromatids
to the opposite poles of the cell

Now there are two!
1.Chromosomes uncoil
2.Spindle fibres disintegrate
3.Centrioles replicate
4.Nucleur membrane forms
5.Cell divides

4 daughter cells produced
Each daughter cell has half the
chromosomes of the parent
2 sets of cell division involved

Chromosome abnormality
Paternal (%) Maternal (%)
Trisomy 21 (Down) 15 85
Trisomy 18 (Edwards) 10 90
Trisomy 13 (Patau) 15 85
45,X (Turner) 80 20
47,XXX 5 95
47,XXY 45 55
47,XYY 100 0

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